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Natural Relief. Hyland's Leg Cramps (logo). Stop the Pain!
#1 Pharmacist recommended brand 2012-2013 - US News Pharmacy Times

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Health Care Providers

Learn more about the diagnosis of leg cramps and treatment options.

Which product is
right for you?

Leg Cramps

  • Stops the cramping pain in limbs and joints including in calves, feet, ankles, legs, hips and thighs
  • Can be taken anytime day or night

Leg Cramps PM

  • Relieves cramps in legs, calves, feet and toes
  • Relieves charley horse cramps in thighs & calves at night
  • Helps you get back to sleep after being awoken by pain during night

Restful Legs

  • Relieves constant urge to move legs
  • Alleviates agitated legs while lying down

Hyland’s Leg Cramps and Leg Cramps PM are Safe & Effective

On July 8, 2010, the FDA issued a drug safety communication specifically warning against using prescription malaria medicine Qualaquin™ (324 mg quinine sulfate per dose) for the off-label treatment of nocturnal leg cramps.

Hyland’s is proud to produce America’s #1 selling leg cramp medicine that is – unlike Qualaquin – extremely safe to use as effective treatment for leg, calf, foot and toe cramps.

Leg Cramps Product Line

Hyland’s Leg Cramps products contain approximately 1/1000th of the quinine per dose that FDA permits in 8 ounces of tonic water.* Hyland’s Leg Cramps and Hyland’s Leg Cramps PM also include several other homeopathic active ingredients to assist in the easing of leg cramp pain, providing natural, non-addicting and safe symptom relief.

  • Homeopathic (micro) doses of quinine are safe
  • Does not interact with other medications
  • New Hyland’s Leg Cramps PM is formulated to promote sleep at night, when leg cramp pain is frequently at its worst.

* Two caplets or tablets of Hyland’s Leg Cramps, or two tablets of Hyland’s Leg Cramps PM, contain approximately 1/1000th of the quinine alkaloid that FDA permits in 8 ounces of tonic water. Read and follow all label directions.


At Hyland’s we are dedicated to making safe, effective, and natural healthcare solutions easily accessible to all.

* The uses for our products are based on traditional homeopathic practice. They have not been reviewed by the Food and Drug Administration.
Disclaimer: Unless otherwise indicated, the individuals depicted on this site are models used for illustrative purposes only.
If you have purchased Hyland’s Calms Forté, Hyland’s Teething Tablets, Hyland’s Migraine Headache Relief, Hyland’s Colic Tablets, Hyland’s Leg Cramps with Quinine, Hyland’s Leg Cramps, Hyland’s Defend Cold & Cough Night, Hyland’s Defend Cold & Cough, Hyland’s Cough, or Hyland’s Seasonal Allergy Relief, on or after February 9, 2008, please visit the following link to obtain information that may affect your legal rights.